Social amnesia in mice lacking the oxytocin gene - PubMed
WEBWe found that male mice mutant for the oxytocin gene (Oxt-/-) failed to develop social memory, whereas wild-type (Oxt+/+) mice showed intact social memory. Measurement of both olfactory foraging and olfactory habituation tasks indicated that olfactory detection of non-social stimuli is intact in Oxt-/- mice.
Social amnesia in mice lacking the oxytocin gene - Nature
WEBWe found that male mice mutant for the oxytocin gene (Oxt −/−) failed to develop social memory, whereas wild-type (Oxt +/+) mice showed intact social memory.
Rescue of oxytocin response and social behaviour in a mouse ... - Nature
WEBAug 5, 2020 · Treatment of Nlgn3 -knockout mice with a new, highly specific, brain-penetrant inhibitor of MAP kinase-interacting kinases resets the translation of mRNA and restores oxytocin signalling and...
Oxytocin in the medial amygdala is essential for social recognition in ...
WEBOct 15, 2001 · Oxytocin (OT) knock-out mice fail to recognize familiar conspecifics after repeated social exposures, despite normal olfactory and spatial learning abilities. OT treatment fully restores social recognition.
Oxytocin in the Medial Amygdala is Essential for Social …
WEBOct 15, 2001 · OT knock-out (OTKO) mice fail to display social recognition despite apparently normal olfactory and spatial learning abilities (Ferguson et al., 2000). Because social memory in OTKO mice is rescued by a single intracerebroventricular infusion of OT, the recognition deficit appears to be attributable …
Absence of oxytocin gene causes social amnesia in mice
WEBJul 1, 2000 · Ferguson and colleagues' “knockout” mice, which lacked the oxytocin gene, showed no tapering off of the investigative behaviour when presented with a stranger, and went through equally thorough sniffing on meeting the same animal for a second time.
Using Transgenic Mouse Models to Study Oxytocin’s Role in the ...
WEBDec 10, 2010 · Male oxytocin KO mice fail to dishabituate to repeated presentations of ovariectomized females, an impairment that is rescued by the administration of oxytocin (Ferguson et al., 2000). The presence of oxytocin in the amygdala appears to play a key role in social recognition: wildtype (WT) but not oxytocin KO mice show activation of c …
Social amnesia in mice lacking the oxytocin gene. - Europe PMC
WEBJul 1, 2000 · We found that male mice mutant for the oxytocin gene (Oxt-/-) failed to develop social memory, whereas wild-type (Oxt+/+) mice showed intact social memory. Measurement of both olfactory foraging and olfactory habituation tasks indicated that olfactory detection of non-social stimuli is intact in Oxt-/- mice.
Social amnesia in mice lacking the OXT gene - ResearchGate
WEBAug 1, 2000 · We found that male mice mutant for the oxytocin gene (Oxt-/-) failed to develop social memory, whereas wild-type (Oxt+/+) mice showed intact social memory.
WEBWe found that male mice mutant for the oxytocin gene (Oxt–/–) failed to develop social memory, whereas wild-type (Oxt+/+) mice showed intact social memory. Measurement of both olfactory foraging and olfactory habituation tasks indicated that olfactory detection of non-social stimuli is intact in Oxt–/– mice.
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