The EMBO Journal4h
Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway
To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...
The EMBO Journal10d
Gene therapy for epilepsy targeting neuropeptide Y and its Y2 receptor to dentate gyrus granule cells
Co-expressing NPY and its inhibitory receptor Y2 in excitatory hippocampal cells allows inhibitory autoregulation of ...
eLife4d
Serotonin modulates infraslow oscillation in the dentate gyrus during Non-REM sleep
In this study, we investigated the neuronal activity of the dentate gyrus (DG) with electrophysiological and optical imaging tools during sleep-wake cycles. We found that the activity of major ...
eLife8d
CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function
CUTS is a cryptic exon RNA biosensor enabling real-time detection of TDP-43 loss of splicing function. CUTS exhibits a significant linear relationship with TDP-43 loss. CUTS can deliver an ...