In a recent article, researchers introduced destabilized near-infrared (NIR) fluorescent nanobodies, offering enhanced ...

This study uncovers how oligodendroglial lipid metabolism supports myelin homeostasis and axonal function under metabolic ...

Cancer has been described as "a wound that does not heal," implying that the immune system is unable to wipe out invading tumor cells. A new discovery confirms that a key molecule can reprogram immune ...

However, whether BCAS2 has other functions within the nucleus remains largely unknown. Here, we show that BCAS2 is essential for primitive hematopoiesis in zebrafish and mouse embryos. The activation ...

CUTS is a cryptic exon RNA biosensor enabling real-time detection of TDP-43 loss of splicing function. CUTS exhibits a significant linear relationship with TDP-43 loss. CUTS can deliver an ...

Co-expressing NPY and its inhibitory receptor Y2 in excitatory hippocampal cells allows inhibitory autoregulation of ...

A review highlighting recent advances in genetically encoded fluorescent tools for labeling and selectively manipulating ...

The bacterial sensors are connected to a green fluorescent protein and the bacteria will glow green ... In the healthy organisms (mice), the molecules glow red, but in organisms with acidic conditions ...

Methods Mice were bilaterally injected with adeno-associated viral vectors expressing mHTT, TDP-43 or green fluorescent protein into the hypothalamus. Body weight was monitored at either 6 or 10 weeks ...